Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828098 | 1.00 | GPR84 (0.39) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL20723734 | 0.97 | GPR84 (0.35) | GPR84FFAR1FFAR4CA2NTRK2 | |
| SCHEMBL2913454 | 0.90 | CA12 (0.33) | CA2 | |
| SCHEMBL194060 | 0.90 | NTRK2 (0.36) | GPR84FFAR1FFAR4NTRK2CAMK2A | |
| SCHEMBL11361410 | 0.88 | CA2 (0.34) | GPR84FFAR1FFAR4CA2NTRK2 | |
| SCHEMBL11313988 | 0.87 | CA12 (0.35) | CA2 | |
| SCHEMBL2843504 | 0.85 | NTRK2 (0.34) | CA2NTRK2CAMK2A | |
| SCHEMBL28498069 | 0.81 | GPR84 (0.36) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL11210472 | 0.81 | GPR84 (0.36) | GPR84FFAR1FFAR4KDM4ESMN1; SMN2 | |
| SCHEMBL8340898 | 0.81 | CA12 (0.44) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202987-A | CHAIN EXTENDERS AND CROSSLINKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |