Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912683 | 0.94 | KMT2A (0.50) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL30193576 | 0.94 | KMT2A (0.50) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL721141 | 0.76 | KMT2A (0.47) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL26049788 | 0.74 | KMT2A (0.46) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL28298483 | 0.74 | KMT2A (0.42) | KMT2ADAOMCL1NPC1RAB9A | |
| SCHEMBL6472453 | 0.73 | SMN1; SMN2 (0.45) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL20436870 | 0.73 | DAO (0.46) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL13665375 | 0.73 | DAO (0.46) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL17321511 | 0.73 | DAO (0.46) | KMT2ACA12CA9DAOMCL1 | |
| SCHEMBL27903386 | 0.71 | LMNA (0.44) | KMT2AALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008556-A1 | Bis 7H pyridocarbazole derivatives and pharmaceutical compositions containing them | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1980-03-05 | — | — | EP | disclosed |