Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166199 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL8200644 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL4935034 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL11475987 | 0.81 | RAB9A (0.38) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL1967325 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL13343437 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL11475992 | 0.80 | RAB9A (0.35) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL13343376 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL13343540 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGAAPOLB | |
| SCHEMBL11499215 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159377-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1979-06-26 | — | — | US | claimed |
| US-4234581-A | ANTIALLERGENS | MEAD JOHNSON & COMPANY (US) | 1980-11-18 | — | — | US | disclosed |