Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RPA1 | P27694 | 3/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869331 | 1.00 | PDK1 (0.41) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL336573 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL26654312 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL27389498 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL9471834 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL6228232 | 0.88 | PTPN1 (0.35) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL678124 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL31438077 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL12547269 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA | |
| SCHEMBL20061642 | 0.88 | PTPN1 (0.43) | PDK1PDK2PDK3PDK4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210671-A | Abietamide derivatives, their production and use | ENOMOTO HIROSHI (JP) | 1980-07-01 | — | — | US | disclosed |
| US-4009206-A | CHOLESTEROL LOWERING AGENTS | MURAI HIROMU | 1977-02-22 | — | — | US | disclosed |