Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.35 |
| ▸ | RPA1 | P27694 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12547269 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL26654312 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL27389498 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL20061642 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL9471834 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL336573 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL678124 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL31438077 | 0.90 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 | |
| SCHEMBL6869331 | 0.88 | PDK1 (0.41) | PTPN1RPA1CYP2C9F10TP53 | |
| Ammonia Solution, Strong SCHEMBL4774266 | 0.88 | PTPN1 (0.43) | PTPN1RPA1CYP2C9F10HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194390-A | — | — | None | — | — | JP | disclosed |
| EP-1122276-B1 | A novel silicone compound and a makeup containing this compound | SHINETSU CHEMICAL CO (JP) | 2005-03-16 | — | — | EP | disclosed |
| US-6759031-B2 | AN ALICYCLIC EPOXY-MODIFIED SILICONE IS SYNTHESIZED BY AN ADDITION REACTION OF A MAIN CHAIN SILOXANE WHICH IS AN ORGANOHYDROGEN POLYSILOXANE TO A VINYL ALICYCLIC EPXOXIDE, AND A SATURATED OR UNSATURATED CARBOXYLIC ACID | SHI-ETSU CHEMICAL CO., LTD. (JP) | 2004-07-06 | — | — | US | disclosed |
| US-6479686-B2 | GOOD SKIN ADHESION, RETENTION, EXCELLENT EMULSION STABILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-20020159964-A1 | Novel silicone compound, and a makeup containing this compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-10-31 | — | — | US | disclosed |
| US-20010014312-A1 | Novel silicon compound, and a makeup containing this compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-16 | — | — | US | disclosed |
| EP-1122276-A2 | A novel silicone compound and a makeup containing this compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0535509-B1 | Monomeric hindered amine esters of monocarboxylic resin acids and olefin polymer compositions stabilized therewith | MONTELL NORTH AMERICA INC (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0362860-B1 | Alcohol-modified silicone ester derivative and cosmetic composition containing same | KAO CORP (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-5417967-A | Alcohol-modified silicone ester derivative and cosmetic compositions containing same | KAO CORPORATION (JP) | 1995-05-23 | — | — | US | disclosed |
| US-5397820-A | Polypropylene | HIMONT INCORPORATED (US) | 1995-03-14 | — | — | US | disclosed |
| US-5334372-A | Improved feel on use | KAO CORPORATION (JP) | 1994-08-02 | — | — | US | disclosed |
| JP-H05194390-A | MONOMERIC HINDERED AMINE ESTER OF MONOCARBOXYLIC RESIN ACID AND OLEFIN POLYMER COMPOSITION STABILIZED WITH THE SAME | HIMONT INC | 1993-08-03 | — | — | JP | disclosed |
| EP-0535509-A1 | Monomeric hindered amine esters of monocarboxylic resin acids and olefin polymer compositions stabilized therewith | MONTELL NORTH AMERICA INC. (US) | 1993-04-07 | — | — | EP | disclosed |
| US-5169949-A | Unsaturated alkyl piperidinyl esters as stabilizer agents for addition polymers; radiation resistance, discoloration inhibition | HIMONT INCORPORATED (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0362860-A2 | Alcohol-modified silicone ester derivative and cosmetic composition containing same | KAO CORPORATION (JP) | 1990-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014312-A1 | Novel silicon compound, and a makeup containing this compound | LOXL1, SAAL1, ACVRL1 | PTPN1 4344/4885RPA1 215/4885HSP90AA1 3440/4885 |
| US-20020159964-A1 | Novel silicone compound, and a makeup containing this compound | SAAL1, ITGB1, ITGB4 | PTPN1 4448/4885RPA1 252/4885HSP90AA1 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.