Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.65 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680087 | 0.88 | TOP2A (0.54) | TOP2ANQO2GPR3GABRPGABRD | |
| SCHEMBL25994750 | 0.88 | TOP2A (0.57) | TOP2ANQO2GPR3GABRPGABRD | |
| SCHEMBL30772924 | 0.81 | GPR3 (0.58) | TOP2ANQO2GPR3GABRPGABRD | |
| SCHEMBL9535679 | 0.81 | GPR3 (0.58) | TOP2ANQO2GPR3GABRPGABRD | |
| SCHEMBL25680013 | 0.81 | TOP2A (0.47) | TOP2ACYP11B2MAOAMAOBACHE | |
| SCHEMBL25703670 | 0.78 | TOP2A (0.54) | TOP2AGPR3GABRPGABRDGABRA1 | |
| SCHEMBL280028 | 0.78 | GPR3 (0.64) | TOP2AGPR3GABRPGABRDGABRA1 | |
| SCHEMBL29548306 | 0.78 | GPR3 (0.64) | TOP2AGPR3GABRPGABRDGABRA1 | |
| SCHEMBL17051459 | 0.77 | GPR3 (0.52) | TOP2ANQO2GPR3GABRPGABRD | |
| SCHEMBL18381818 | 0.76 | GPR3 (0.61) | TOP2AGPR3GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008556-A1 | Bis 7H pyridocarbazole derivatives and pharmaceutical compositions containing them | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1980-03-05 | — | — | EP | disclosed |