Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499481 | 0.88 | TOP2A (0.65) | TOP2AMAPTMAOAMAOBACHE | |
| SCHEMBL25994750 | 0.84 | TOP2A (0.57) | TOP2AMAPTMAOAMAOBACHE | |
| SCHEMBL30772924 | 0.81 | GPR3 (0.58) | TOP2ARAB9AMAPTCASP1ACHE | |
| SCHEMBL9535679 | 0.81 | GPR3 (0.58) | TOP2ARAB9AMAPTCASP1ACHE | |
| SCHEMBL19271269 | 0.81 | MAOA (0.46) | TOP2ARAB9ANPC1TP53MAPT | |
| SCHEMBL30772964 | 0.79 | GPR3 (0.52) | RAB9AMAPTCASP1GPR3ATM | |
| SCHEMBL10023491 | 0.79 | GPR3 (0.52) | RAB9AMAPTCASP1GPR3ATM | |
| SCHEMBL25703708 | 0.78 | TOP2A (0.47) | TOP2ARAB9ANPC1TP53MAPT | |
| SCHEMBL29548306 | 0.78 | GPR3 (0.64) | TOP2AMAPTMAOAMAOBACHE | |
| SCHEMBL280028 | 0.78 | GPR3 (0.64) | TOP2AMAPTMAOAMAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004061416-A2 | METHODS FOR ATTACHING MOLECULES | GENORX, INC. (US) | 2004-07-22 | — | — | WO | claimed |
| US-20040048241-A1 | Methods for attaching molecules | GENORX, INC. | 2004-03-11 | — | — | US | claimed |
| WO-2004061133-A1 | ASSOCIATION OF MOLECULES WITH ELECTRODES OF AN ARRAY OF ELECTRODES | GENORX, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| WO-2004061416-A2 | METHODS FOR ATTACHING MOLECULES | GENORX, INC. (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040048241-A1 | Methods for attaching molecules | GENORX, INC. | 2004-03-11 | — | — | US | disclosed |
| US-20030224387-A1 | Association of molecules with electrodes of an array of electrodes | GENORX, INC. | 2003-12-04 | — | — | US | disclosed |