SCHEMBL1150004

SCHEMBL1150004

Cc1ccccc1CC(=O)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.55
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
SHBG P04278 1/20 0.47
HPGD P15428 2/20 0.46
ALDH1A1 P00352 1/20 0.46
NPC1 O15118 2/20 0.45
CASP3 P42574 1/20 0.44
CASP7 P55210 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
MAPK8 P45983 1/20 0.43
RAB9A P51151 1/20 0.42
CACNA1G O43497 1/20 0.42
CACNA1H O95180 1/20 0.42
CACNA1I Q9P0X4 1/20 0.42
HTT P42858 1/20 0.42
GAA P10253 1/20 0.42
MAOB P27338 1/20 0.42
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL7260822 0.91 CTBP2 (0.51) CTBP2KMT2AMEN1MAPTSHBG
SCHEMBL6767819 0.84 AKR1B1 (0.46) CTBP2ALDH1A1NPC1RAB9APTGS2
SCHEMBL7405623 0.83 P2RX7 (0.44) CTBP2KMT2AMEN1MAPTALDH1A1
SCHEMBL158861 0.83 CTBP2 (0.55) CTBP2KMT2AMEN1MAPTSHBG
SCHEMBL29718576 0.83 CTBP2 (0.55) CTBP2KMT2AMEN1MAPTSHBG
SCHEMBL2935824 0.82 CTBP2 (0.58) CTBP2KMT2AMEN1MAPTSHBG
Hydrochloric Acid SCHEMBL14167478 0.81 CTBP2 (0.53) CTBP2KMT2AMEN1MAPTSHBG
SCHEMBL24977628 0.80 GABRA1 (0.44) SHBGALDH1A1PTGS2
SCHEMBL2528595 0.80 AKR1B1 (0.61) CTBP2KMT2AMEN1MAPTSHBG
SCHEMBL8285 0.80 AKR1B1 (0.61) CTBP2KMT2AMEN1MAPTSHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111635435-B Bivalent copper complex containing biphosphine ortho-carborane ligand, and preparation method and application thereof 上海应用技术大学 2023-04-28 CN claimed
EP-1931693-A2 PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES CHEMAGIS LTD. (IL) 2008-06-18 EP claimed
WO-2007027564-A2 PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES CHEMAGIS LTD. (IL) 2007-03-08 WO claimed
CN-119528934-A 2-Pyridothiophene compound, preparation method, application and antitubercular drug thereof 桂林医学院 2025-02-28 CN disclosed
CN-119241469-A Photoinitiator, photopolymerization composition and application thereof 武汉尚赛光电科技有限公司 2025-01-03 CN disclosed
US-20240417379-A1 P2X4 RECEPTOR ANTAGONIST NIPPON CHEMIPHAR CO., LTD (JP) 2024-12-19 US disclosed
US-12116351-B2 P2X4 receptor antagonist NIPPON CHEMIPHAR CO., LTD (JP) 2024-10-15 US disclosed
EP-4430026-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2024-09-18 EP disclosed
US-20240000075-A1 FUNGICIDAL ARYL AMIDINES CORTEVA AGRISCIENCE LLC (US) 2024-01-04 US disclosed
CN-117024298-A Tertiary amide compound containing naphthyl and its preparation method and application 北京中医药大学 2023-11-10 CN disclosed
EP-4247788-A1 FUNGICIDAL ARYL AMIDINES Corteva Agriscience LLC (US) 2023-09-27 EP disclosed
US-4210749-A USED AS ANALGESICS, NARCOTIC ANTAGONISTS PENNWALT CORPORATION (US) 1980-07-01 US disclosed
US-4200572-A Substituted azetidinones SMITHKLINE CORPORATION (US) 1980-04-29 US disclosed
US-4148918-A APHICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-10 US disclosed
US-4115584-A Substituted 2-higher alkyl-3-hydroxy-1,4-naphthoquinone carboxylic acid esters and their use as miticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-19 US disclosed
US-4086423-A CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND MERCK & CO., INC. (US) 1978-04-25 US disclosed
US-4070481-A Substituted 2-higher alkyl-3-hydroxy-1,4-naphthoquinone carboxylic acid esters and their use as miticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-01-24 US disclosed
US-4008276-A ANTIINFLAMMATORY STERLING DRUG INC. (US) 1977-02-15 US disclosed
US-4000154-A 3-Substituted-6β-(amino- and acylamino)-7-oxo-1,3-diazabicyclo[3.2.0]-h SMITHKLINE CORPORATION (US) 1976-12-28 US disclosed
US-3965105-A ANTIINFLAMMATORY STERLING DRUG INC. (US) 1976-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240000075-A1 FUNGICIDAL ARYL AMIDINES CYP1A1, CYP1A2, CYP1B1 CTBP2 3916/4885KMT2A 1220/4885MEN1 1445/4885
US-20240417379-A1 P2X4 RECEPTOR ANTAGONIST P2RX7, P2RX1, P2RX2 CTBP2 2980/4885KMT2A 2558/4885MEN1 3285/4885
US-12116351-B2 P2X4 receptor antagonist P2RX7, P2RX1, P2RX2 CTBP2 3253/4885KMT2A 2174/4885MEN1 3450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.