Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090096 | 0.81 | MCL1 (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12085149 | 0.77 | TSHR (0.62) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL3988292 | 0.77 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL23583597 | 0.72 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL19791941 | 0.71 | MCL1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL13739822 | 0.70 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL11496932 | 0.70 | TSHR (0.32) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL338964 | 0.70 | — | — | |
| SCHEMBL8413847 | 0.70 | MCL1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL13227318 | 0.70 | ALDH1A1 (0.36) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017703-A1 | Copolymerizable (2-cyano-3,3-diarylacryloxy)alkylene compounds, a method of making them and the use of these compounds as ultraviolet light absorbers | GAF CORPORATION (US) | 1980-10-29 | — | — | EP | claimed |
| US-4218392-A | Two-step method of making copolymerizable, ultraviolet light absorber _2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters | GAF CORPORATION (US) | 1980-08-19 | — | — | US | claimed |
| EP-0017703-A1 | Copolymerizable (2-cyano-3,3-diarylacryloxy)alkylene compounds, a method of making them and the use of these compounds as ultraviolet light absorbers | GAF CORPORATION (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4218392-A | Two-step method of making copolymerizable, ultraviolet light absorber _2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters | GAF CORPORATION (US) | 1980-08-19 | — | — | US | disclosed |
| US-4178303-A | (2-Cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters | GAF CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |