Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | RRM2 | P31350 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99646 | 0.84 | CA12 (0.65) | CA12CA1CA2CA9RRM2 | |
| SCHEMBL2297932 | 0.83 | CA12 (0.55) | CA12CA1CA2CA9RRM2 | |
| SCHEMBL4256276 | 0.81 | CA12 (0.53) | CA12CA1CA2CA9RRM2 | |
| SCHEMBL174596 | 0.78 | CA1 (0.55) | CA12CA1CA2CA9RRM2 | |
| SCHEMBL1585896 | 0.78 | CA12 (0.59) | CA12CA1CA2CA9RRM2 | |
| SCHEMBL11304749 | 0.77 | CA12 (0.50) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL11297320 | 0.77 | FFAR1 (0.53) | CA12CA1CA2CA9TSHR | |
| Water SCHEMBL11215220 | 0.76 | CA12 (0.57) | CA12CA1CA2CA9RRM2 | |
| SCHEMBL22873353 | 0.75 | TSHR (0.43) | CA12CA1CA2CA9CA4 | |
| SCHEMBL5958592 | 0.75 | ALDH1A1 (0.52) | CA12CA1CA2CA9RRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198522-A | HYPOLIPIDEMIC ACND ANTI-ATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-15 | — | — | US | disclosed |