SCHEMBL2297932

SCHEMBL2297932

C=CCNc1ccc(Cc2ccc(NCC=C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
LMNA P02545 3/20 0.38
HPGD P15428 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
TEAD4 Q15561 1/20 0.36
RRM2 P31350 1/20 0.36
SAE1 Q9UBE0 2/20 0.35
UBA2 Q9UBT2 2/20 0.35
TSHR P16473 1/20 0.35
ADRA2A P08913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5958592 0.90 ALDH1A1 (0.52) CA12CA1CA2CA9ALDH1A1
SCHEMBL99646 0.88 CA12 (0.65) CA12CA1CA2CA9LMNA
SCHEMBL4256276 0.84 CA12 (0.53) CA12CA1CA2CA9HPGD
SCHEMBL11501100 0.83 CA12 (0.52) CA12CA1CA2CA9HPGD
SCHEMBL11801977 0.82 CA12 (0.55) CA12CA1CA2CA9HPGD
SCHEMBL1585896 0.81 CA12 (0.59) CA12CA1CA2CA9LMNA
Water SCHEMBL11215220 0.79 CA12 (0.57) CA12CA1CA2CA9LMNA
SCHEMBL7199847 0.78 CA12 (0.56) CA12CA1CA2CA9LMNA
SCHEMBL4243384 0.77 CA12 (0.55) CA12CA1CA2CA9LMNA
SCHEMBL7717454 0.77 CA1 (0.55) CA12CA1CA2CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5405218-A Method for the repair of existing manholes using elastomeric materials FOAMSEAL INC (US) 1995-04-11 US claimed
US-4960620-A PATCHING PAVEMENT USING A MIXTURE OF ISOCYANATE-POLYOL PREPOLYMER, AN AROMATIC N,N'-ALKYL DIAMINE CURING AGENT, A FATTY ACID AND AN ORGANOMETALLIC CATALYST UOP (US) 1990-10-02 US claimed
US-4874831-A Room-temperature-cured polyurethanes and polyureas UOP (US) 1989-10-17 US claimed
US-4783517-A Polyureas as coatings UOP INC. (US) 1988-11-08 US claimed
US-4714512-A N,N'-DIALKYLMETHYLENEDIANILINE CURING AGENT UOP INC. (US) 1987-12-22 US claimed
US-4663201-A BIURET CONTAINING UOP INC. (US) 1987-05-05 US claimed
JP-56115783-A None JP disclosed
EP-2178828-B1 ALDIMINES AND COMPOUNDS CONTAINING ALDIMINE SIKA TECH AG (CH) 2019-06-26 EP disclosed
US-9902803-B2 Epoxy compound having alkoxy silyl group, composition comprising same, cured product, use thereof and method for preparing epoxy compound having alkoxy silyl group KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-27 US disclosed
US-9902803-B2 Epoxy compound having alkoxy silyl group, composition comprising same, cured product, use thereof and method for preparing epoxy compound having alkoxy silyl group KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2018-02-27 US disclosed
EP-2651875-B1 AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-30 EP disclosed
EP-2651876-B1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-09 EP disclosed
US-20150368509-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2015-12-24 US disclosed
US-4874831-A Room-temperature-cured polyurethanes and polyureas UOP (US) 1989-10-17 US disclosed
US-4720536-A Blends of secondary alkyl aromatic diamines and polyhydric alcohols as curing agents in polyurethane manufacture UOP INC. (US) 1988-01-19 US disclosed
US-4714512-A N,N'-DIALKYLMETHYLENEDIANILINE CURING AGENT UOP INC. (US) 1987-12-22 US disclosed
US-4709003-A CURING URETHANE PREPOLYMERS UOP INC. (US) 1987-11-24 US disclosed
US-4663201-A BIURET CONTAINING UOP INC. (US) 1987-05-05 US disclosed
US-4578446-A Secondary aromatic diamines as curing agents in polyurethane manufacturing UOP INC. (US) 1986-03-25 US disclosed
JP-S56115783-A PREPARATION OF DIISOBUTENYLSUCCINIC ANHYDRIDE GOI KASEI KK 1981-09-11 JP disclosed