SCHEMBL11501236

SCHEMBL11501236

O=C(c1ccccc1)c1cccc(C(=O)c2c(C(=O)O)c(C(=O)O)c(C(=O)O)c(C(=O)O)c2C(=O)O)c1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.67
MYC P01106 1/20 0.57
CDC25B P30305 2/20 0.53
ATM Q13315 2/20 0.53
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
NR4A1 P22736 1/20 0.52
POLB P06746 1/20 0.51
ALDH1A1 P00352 1/20 0.50
CDC25A P30304 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SRD5A2 P31213 1/20 0.48
CYP2C8 P10632 1/20 0.47
CYP2C9 P11712 1/20 0.47
KDM4E B2RXH2 1/20 0.47
DAO P14920 1/20 0.44
TSHR P16473 1/20 0.44
NAPRT Q6XQN6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8605058 0.94 AKR1C3 (0.64) AKR1C3MYCCDC25BATMGAA
SCHEMBL144047 0.90 AKR1C3 (0.76) AKR1C3MYCCDC25BATMGAA
SCHEMBL30978151 0.90 AKR1C3 (0.76) AKR1C3MYCCDC25BATMGAA
Hydrochloric Acid SCHEMBL10626938 0.88 AKR1C3 (0.73) AKR1C3MYCCDC25BATMGAA
SCHEMBL857849 0.85 AKR1C3 (0.67) AKR1C3MYCCDC25BATMGAA
SCHEMBL28533570 0.85 ALDH1A1 (0.68) AKR1C3CDC25BATMGAAMAPT
SCHEMBL11443685 0.85 ALDH1A1 (0.68) AKR1C3CDC25BATMGAAMAPT
SCHEMBL31432550 0.83 AKR1C3 (0.72) AKR1C3MYCCDC25BATMGAA
SCHEMBL425272 0.83 AKR1C3 (0.65) AKR1C3MYCCDC25BATMGAA
SCHEMBL9774810 0.83 AKR1C3 (0.64) AKR1C3MYCCDC25BATMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4235787-A ISOMERIC MIXTURE; CROSSLINKING WITH EPONS\ GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-11-25 US disclosed