SCHEMBL425272

SCHEMBL425272

O=C(O)c1cccc(C(=O)c2ccc(C(=O)c3cccc(C(=O)O)c3C(=O)O)cc2)c1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.65
CDC25B P30305 3/20 0.62
ATM Q13315 1/20 0.62
NR4A1 P22736 1/20 0.60
CDC25A P30304 1/20 0.57
HSD17B10 Q99714 1/20 0.57
MYC P01106 1/20 0.51
ALDH1A1 P00352 3/20 0.50
POLB P06746 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
ALOX15 P16050 1/20 0.48
SRD5A2 P31213 2/20 0.46
CYP2C8 P10632 1/20 0.46
CYP2C9 P11712 1/20 0.46
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23501588 0.96 AKR1C3 (0.61) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL144047 0.94 AKR1C3 (0.76) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL30978151 0.94 AKR1C3 (0.76) AKR1C3CDC25BATMNR4A1CDC25A
Hydrochloric Acid SCHEMBL10626938 0.92 AKR1C3 (0.73) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL21247044 0.91 AKR1C3 (0.55) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL147496 0.89 CDC25B (0.55) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL29882813 0.89 CDC25B (0.55) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL426276 0.88 AKR1C3 (0.61) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL9327249 0.88 CA1 (0.55) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL31432550 0.87 AKR1C3 (0.72) AKR1C3CDC25BATMNR4A1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115852699-B Preparation method of photodynamic chargeable antibacterial antiviral nanofiber membrane 天津工业大学 2023-10-03 CN disclosed
CN-115852699-A Preparation method of photodynamic rechargeable antibacterial antiviral nanofiber membrane 天津工业大学 2023-03-28 CN disclosed
CN-110431696-B Binder composition for secondary battery 日本电气株式会社 2022-12-06 CN disclosed
CN-109563282-B Medical film and method for producing same, medical coating composition, medical device and method for producing same 三井化学株式会社 2022-04-15 CN disclosed
US-11198280-B2 Medical film and method for producing same, medical coating composition, medical device and method for producing same MITSUI CHEMICALS, INC. (JP) 2021-12-14 US disclosed
US-11018341-B2 Binder composition for secondary battery NEC CORPORATION (JP) 2021-05-25 US disclosed
US-10707491-B2 Binder for secondary battery NEC CORPORATION (JP) 2020-07-07 US disclosed
US-20200129377-A1 MEDICAL FILM AND METHOD FOR PRODUCING SAME, MEDICAL COATING COMPOSITION, MEDICAL DEVICE AND METHOD FOR PRODUCING SAME MITSUI CHEMICALS, INC. (JP) 2020-04-30 US disclosed
US-10351673-B2 Block polyimide, block polyamide acid imide and use thereof MITSUI CHEMICALS, INC. (JP) 2019-07-16 US disclosed
EP-3489285-A1 MEDICAL FILM AND METHOD FOR PRODUCING SAME, MEDICAL COATING COMPOSITION, MEDICAL DEVICE AND METHOD FOR PRODUCING SAME Mitsui Chemicals, Inc. (JP) 2019-05-29 EP disclosed
US-9339992-B2 Low-thermal-expansion block polyimide, precursor thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2016-05-17 US disclosed
US-20160075830-A1 BLOCK POLYIMIDE, BLOCK POLYAMIDE ACID IMIDE AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2016-03-17 US disclosed
US-20160053135-A1 POLYAMIC ACID, VARNISH CONTAINING SAME, AND POLYIMIDE FILM MITSUI CHEMICAL, INC. (JP) 2016-02-25 US disclosed
US-20160032055-A1 POLYAMIC ACID, VARNISH COMPRISING SAME AND POLYIMIDE FILM MITSUI CHEMICALS., INC. (JP) 2016-02-04 US disclosed
US-20120021234-A1 LOW-THERMAL-EXPANSION BLOCK POLYIMIDE, PRECURSOR THEREOF, AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2012-01-26 US disclosed
US-20110318588-A1 POLYAMIC ACID AND POLYIMIDE, PROCESSES FOR THE PRODUCTION OF SAME, COMPOSITONS CONTAINING SAME, AND USES THEREOF Mitsu Chemicals Inc, (TK) 2011-12-29 US disclosed
EP-1225192-B1 POLYIMIDES AND POLYAMIC ACIDS MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
US-6599675-B2 Useful for application of photoresist, as an insulation film; heat resistance, mechanical properties and adhesion property MITSUI CHEMICALS, INC. (JP) 2003-07-29 US disclosed
US-20020182536-A1 Polyimides and polyamic acids MITSUI CHEMICALS, INC. (JP) 2002-12-05 US disclosed
EP-1225192-A1 POLYIMIDES AND POLYAMIC ACIDS Mitsui Chemicals, Inc. (JP) 2002-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110318588-A1 POLYAMIC ACID AND POLYIMIDE, PROCESSES FOR THE PRODUCTION OF SAME, COMPOSITONS CONTAINING SAME, AND USES THEREOF ASS1, TAF1, CPSF1 AKR1C3 2274/4885CDC25B 3675/4885ATM 3222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.