Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499581 | 0.88 | NLRP3 (0.44) | NLRP3POLBMAPK1PTGS2RAB9A | |
| Glycine SCHEMBL11340116 | 0.87 | PTGS2 (0.42) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11283120 | 0.86 | NLRP3 (0.40) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11500154 | 0.86 | NLRP3 (0.40) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11498543 | 0.86 | NLRP3 (0.40) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11274955 | 0.85 | NLRP3 (0.42) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11377106 | 0.85 | NLRP3 (0.39) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11498945 | 0.84 | NLRP3 (0.41) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11285528 | 0.84 | NLRP3 (0.41) | NLRP3POLBMAPK1PTGS2RAB9A | |
| SCHEMBL11332191 | 0.84 | NLRP3 (0.46) | NLRP3POLBMAPK1PTGS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009569-A1 | Oxalyl derivatives of N-phenylaminocarboxylic acids (and their esters), processes for their preparation and their use as fungicides | BAYER AG (DE) | 1980-04-16 | — | — | EP | disclosed |