Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717852 | 0.86 | LMNA (0.38) | LMNACARM1PRMT6PRMT8ATM | |
| SCHEMBL951037 | 0.84 | TDP1 (0.34) | LMNACARM1PRMT6PRMT8ATM | |
| SCHEMBL2783147 | 0.84 | CYP2D6 (0.43) | LMNACARM1PRMT6PRMT8ATM | |
| SCHEMBL7050630 | 0.84 | LMNA (0.36) | LMNACARM1PRMT6PRMT8ATM | |
| SCHEMBL3272365 | 0.84 | ATM (0.34) | LMNACARM1PRMT6PRMT8ATM | |
| SCHEMBL12718302 | 0.84 | ALDH1A1 (0.37) | LMNAHRH3TSHRALDH1A1MEN1 | |
| SCHEMBL24926235 | 0.82 | HRH3 (0.33) | CARM1PRMT6PRMT8ATMHRH3 | |
| SCHEMBL2904075 | 0.82 | HRH3 (0.33) | CARM1PRMT6PRMT8ATMHRH3 | |
| SCHEMBL6443996 | 0.82 | TSHR (0.36) | ATMHRH3TDP1TSHRALDH1A1 | |
| SCHEMBL6445428 | 0.82 | TSHR (0.36) | ATMHRH3TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156603-A | COMPLEXED WITH A POLYFUNCTIONAL LEWIS BASE | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4152401-A | Chelated lithium aluminum compounds | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4147530-A | Reductions of inorganic substrates with chelated sodium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4094876-A | OIL AND FUEL ADDITIVES | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4088666-A | Reductions with chelated lithium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-05-09 | — | — | US | disclosed |
| US-3933879-A | SEPARATIONS, CATALYTIC REACTIONS, REDUCTIONS, ELECTROCHEMISTRY | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1976-01-20 | — | — | US | disclosed |