Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501717 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL11501743 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL11501744 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL11501952 | 0.71 | ALDH1A1 (0.65) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL11501954 | 0.71 | ALDH1A1 (0.65) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL10738197 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL9146862 | 0.67 | CYP3A4 (0.59) | ALDH1A1MAPTTDP1KMT2ACYP3A4 | |
| SCHEMBL28027871 | 0.64 | ALDH1A1 (0.64) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL1987675 | 0.64 | CYP3A4 (0.71) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL31432619 | 0.64 | MAPT (1.00) | ALDH1A1MAPTTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177271-A | ANTIDEPRESSANTS, HYPNOTICS | UNICLER (FR) | 1979-12-04 | — | — | US | claimed |
| US-4177271-A | ANTIDEPRESSANTS, HYPNOTICS | UNICLER (FR) | 1979-12-04 | — | — | US | disclosed |