Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501744 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EALOX15HPGDLMNA | |
| SCHEMBL11501994 | 0.75 | HSP90AA1 (0.55) | ALDH1A1KDM4EALOX15HPGDLMNA | |
| SCHEMBL11501993 | 0.75 | HSP90AA1 (0.55) | ALDH1A1KDM4EALOX15HPGDLMNA | |
| SCHEMBL11501717 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDLMNAMAOB | |
| SCHEMBL11501716 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDLMNAMAOB | |
| SCHEMBL11488275 | 0.68 | MEN1 (0.41) | ALDH1A1KDM4EALOX15LMNAKMT2A | |
| SCHEMBL10738197 | 0.67 | ALDH1A1 (0.46) | ALDH1A1KDM4EALOX15HPGDLMNA | |
| SCHEMBL11483857 | 0.66 | MEN1 (0.38) | ALDH1A1KDM4EALOX15KMT2AMEN1 | |
| SCHEMBL11482203 | 0.65 | MEN1 (0.42) | ALDH1A1KDM4EALOX15LMNADYRK2 | |
| SCHEMBL11478739 | 0.64 | KDM4E (0.67) | ALDH1A1KDM4EALOX15HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177271-A | ANTIDEPRESSANTS, HYPNOTICS | UNICLER (FR) | 1979-12-04 | — | — | US | claimed |
| US-4177271-A | ANTIDEPRESSANTS, HYPNOTICS | UNICLER (FR) | 1979-12-04 | — | — | US | disclosed |