Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423288 | 0.83 | TP53 (0.50) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL10612899 | 0.83 | TP53 (0.50) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL5108877 | 0.81 | TP53 (0.65) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL15053379 | 0.81 | TP53 (0.65) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL30399939 | 0.81 | TP53 (0.65) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL7594119 | 0.80 | TP53 (0.50) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL29700366 | 0.80 | TP53 (0.50) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL23046954 | 0.79 | TP53 (0.47) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL3848475 | 0.79 | TP53 (0.69) | TP53HTTLMNATSHRTDP1 | |
| SCHEMBL20868991 | 0.79 | TP53 (0.69) | TP53HTTLMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156602-A | 1-(1-Chloropropyl)-2,4,6-triisopropylbenzene and its use to control weeds | PPG INDUSTRIES, INC. (US) | 1979-05-29 | — | — | US | disclosed |