SCHEMBL29700366

SCHEMBL29700366

Clc1ccc(Cl)c(C(Cl)Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.50
TSHR P16473 8/20 0.44
CYP3A4 P08684 5/20 0.44
TDP1 Q9NUW8 5/20 0.44
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 3/20 0.41
HTT P42858 1/20 0.41
HIF1A Q16665 2/20 0.38
MAPK1 P28482 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NR1I2 O75469 1/20 0.38
ABCB11 O95342 1/20 0.38
NR3C1 P04150 1/20 0.38
PGR P06401 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594119 1.00 TP53 (0.50) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL9622386 0.81 TP53 (0.43) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL11501929 0.80 TP53 (0.48) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL7560420 0.79 TP53 (0.58) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL29700271 0.79 TP53 (0.58) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL16957103 0.77 TP53 (0.48) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL423288 0.77 TP53 (0.50) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL9854302 0.77 TSHR (0.48) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL10612899 0.77 TP53 (0.50) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL1071628 0.77 TP53 (0.42) TP53TSHRCYP3A4TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552089-A Preparation method of 3-amino-2-fluorobenzoyl chloride and derivatives thereof 帕潘纳(北京)科技有限公司 2025-03-04 CN disclosed
CN-109111463-B Method for producing aromatic compound DIC株式会社 2022-07-01 CN disclosed