Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 4/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501854 | 0.98 | DNM1 (0.43) | DNM1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL10980645 | 0.94 | CA12 (0.36) | DNM1KDM5AKDM4CALDH1A1PHF8 | |
| SCHEMBL11502135 | 0.83 | DNM1 (0.43) | DNM1S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL11502089 | 0.78 | CA12 (0.36) | DNM1KDM5AKDM4CALDH1A1PHF8 | |
| SCHEMBL2178884 | 0.76 | CA12 (0.38) | KDM5AKDM4CALDH1A1PHF8EPHX2 | |
| SCHEMBL10994991 | 0.74 | CA1 (0.36) | DNM1KDM5AKDM4CALDH1A1PHF8 | |
| SCHEMBL10833400 | 0.74 | ALDH1A1 (0.44) | KDM5AKDM4CALDH1A1PHF8CES2 | |
| SCHEMBL10832203 | 0.74 | CA12 (0.33) | KDM4CALDH1A1 | |
| SCHEMBL10659833 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11015892 | 0.70 | CA12 (0.48) | DNM1ALDH1A1ZDHHC20ZDHHC2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151353-A | INSECTICIDE AND MITICIDE INTERMEDIATES | UNION CARBIDE CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |