SCHEMBL11502172

SCHEMBL11502172

C[SiH]([O])CCCOCCC#N

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11501975 0.92 ZDHHC20 (0.31)
SCHEMBL11502303 0.92 TSHR (0.34) TSHR
SCHEMBL11502203 0.81 TSHR (0.37) TSHR
SCHEMBL11502257 0.80 TSHR (0.30) TSHR
SCHEMBL11502186 0.78
SCHEMBL11502129 0.76
SCHEMBL4846035 0.75 ALDH1A1 (0.41) TSHR
SCHEMBL12737606 0.75 ALDH1A1 (0.41) TSHR
SCHEMBL11502205 0.73 TSHR (0.32) TSHR
SCHEMBL11502162 0.73 ZDHHC20 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4138391-A Acrylonitrile-capped polyether-siloxanes UNION CARBIDE CORPORATION (US) 1979-02-06 US disclosed
US-4107068-A USED TO PREPARE CELLULAR POLYURETHANES UNION CARBIDE CORPORATION (US) 1978-08-15 US disclosed
US-4058494-A Polyether urethane foam produced with cyano-ether polysiloxane-polyoxyalkylene copolymers UNION CARBIDE CORPORATION (US) 1977-11-15 US disclosed
US-4058493-A Polyester urethane foam produced with cyano-ether polysiloxane-polyoxyalkylene copolymers UNION CARBIDE CORPORATION (US) 1977-11-15 US disclosed
US-4043951-A Acrylonitrile-capped polyether-siloxane UNION CARBIDE CORPORATION (US) 1977-08-23 US disclosed
US-4012401-A USED IN THE PRODUCTION OF POLYURETHANE FOAMS, CYANOALKOXYALKYL-MODIFIED UNION CARBIDE CORPORATION (US) 1977-03-15 US disclosed
US-3979420-A FLAME RETARDERS FOR POLYETHERURETHANE COPOLYMERS UNION CARBIDE CORPORATION (US) 1976-09-07 US disclosed
US-3979419-A STABILIZERS OF POLYESTER-URETHANE COPOLYMERS, FIREPROOFING UNION CARBIDE CORPORATION (US) 1976-09-07 US disclosed
US-3966784-A CYANOALKYL MODIFIED SILOXANE FLUID UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed
US-3966650-A HIGH RESILIENCE, CYANOALKOXY-ALKYL MODIFIED SILOXANE FLUID UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed
US-3943156-A HYDROSILATION, CONDENSATION UNION CARBIDE CORPORATION (US) 1976-03-09 US disclosed