Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488679 | 0.78 | FAAH (0.38) | FAAHCES1MLYCDALDH1A1PLA2G4B | |
| SCHEMBL11488677 | 0.78 | FAAH (0.38) | FAAHCES1MLYCDALDH1A1PLA2G4B | |
| SCHEMBL11492542 | 0.78 | FAAH (0.44) | FAAHCES1ALDH1A1PLA2G4BMAPT | |
| SCHEMBL11492543 | 0.78 | FAAH (0.44) | FAAHCES1ALDH1A1PLA2G4BMAPT | |
| SCHEMBL11494059 | 0.77 | FAAH (0.43) | FAAHCES1MLYCDALDH1A1PLA2G4B | |
| SCHEMBL11494060 | 0.77 | FAAH (0.43) | FAAHCES1MLYCDALDH1A1PLA2G4B | |
| SCHEMBL11493715 | 0.77 | FAAH (0.43) | FAAHCES1MLYCDALDH1A1PLA2G4B | |
| SCHEMBL11491012 | 0.75 | HDAC6 (0.46) | FAAHCES1MLYCDALDH1A1PLA2G4B | |
| SCHEMBL11493486 | 0.75 | FAAH (0.43) | FAAHCES1MLYCDALDH1A1PLA2G4B | |
| SCHEMBL11493488 | 0.75 | FAAH (0.43) | FAAHCES1MLYCDALDH1A1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |