SCHEMBL11488679

SCHEMBL11488679

CCCCCCCCCC=CCCCN(C(=O)C(F)(F)F)c1ccc(C(=O)ON2C(=O)CCC2=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.38
CES1 P23141 2/20 0.38
MGLL Q99685 2/20 0.37
ALDH1A1 P00352 1/20 0.37
PLA2G4B P0C869 1/20 0.37
MAPT P10636 1/20 0.37
PLA2G4A P47712 1/20 0.37
BLM P54132 1/20 0.37
PLA2G4C Q9UP65 1/20 0.37
MLYCD O95822 6/20 0.35
CCR5 P51681 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11488677 1.00 FAAH (0.38) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11070644 0.92 MLYCD (0.40) FAAHALDH1A1MAPTMLYCD
SCHEMBL11070793 0.83 FAAH (0.37) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11070795 0.83 FAAH (0.37) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11492542 0.81 FAAH (0.44) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11492543 0.81 FAAH (0.44) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11493715 0.80 FAAH (0.43) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11494059 0.80 FAAH (0.43) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11494060 0.80 FAAH (0.43) FAAHCES1MGLLALDH1A1PLA2G4B
SCHEMBL11503201 0.78 FAAH (0.35) FAAHCES1MGLLALDH1A1PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4230878-A AND 4-(UNSATURATED ALKYL)AMINOBENZOIC ACIDS AND DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1980-10-28 US disclosed