SCHEMBL1150328

SCHEMBL1150328

CCC(C)OC(=O)[C@H]1[C@H](C=O)C1(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1150324 1.00 LMNA (0.41) LMNACYP1A2TSHRCYP2C19
SCHEMBL1150325 1.00 LMNA (0.41) LMNACYP1A2TSHRCYP2C19
SCHEMBL1150665 0.82 LMNA (0.39) LMNACYP1A2TSHRCYP2C19
SCHEMBL1150671 0.82 LMNA (0.39) LMNACYP1A2TSHRCYP2C19
SCHEMBL1150668 0.82 LMNA (0.39) LMNACYP1A2TSHRCYP2C19
SCHEMBL357831 0.82 LMNA (0.41) LMNA
SCHEMBL357089 0.81 LMNA (0.40) LMNA
SCHEMBL358752 0.79 LMNA (0.37) LMNACYP1A2TSHRCYP2C19
SCHEMBL359126 0.78 LMNA (0.36) LMNACYP1A2TSHRCYP2C19
SCHEMBL357789 0.76 LMNA (0.39) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7893294-B2 Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-22 US disclosed
US-20090314987-A1 PROCESS FOR PRODUCTION OF TRANS-2, 2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-12-24 US disclosed
EP-2053037-A1 PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER Sumitomo Chemical Company, Limited (JP) 2009-04-29 EP disclosed