Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150665 | 1.00 | LMNA (0.39) | LMNATSHRCYP1A2CYP2C19POLB | |
| SCHEMBL1150668 | 1.00 | LMNA (0.39) | LMNATSHRCYP1A2CYP2C19POLB | |
| SCHEMBL7533541 | 0.89 | LMNA (0.33) | LMNATSHRCYP1A2CYP2C19 | |
| SCHEMBL358752 | 0.85 | LMNA (0.37) | LMNATSHRCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL359126 | 0.84 | LMNA (0.36) | LMNATSHRCYP1A2CYP2C19 | |
| SCHEMBL3690514 | 0.83 | LMNA (0.38) | LMNATSHRCYP1A2CYP2C19POLB | |
| SCHEMBL3690512 | 0.83 | LMNA (0.38) | LMNATSHRCYP1A2CYP2C19POLB | |
| SCHEMBL1150325 | 0.82 | LMNA (0.41) | LMNATSHRCYP1A2CYP2C19 | |
| SCHEMBL1150328 | 0.82 | LMNA (0.41) | LMNATSHRCYP1A2CYP2C19 | |
| SCHEMBL1150324 | 0.82 | LMNA (0.41) | LMNATSHRCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893294-B2 | Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20090314987-A1 | PROCESS FOR PRODUCTION OF TRANS-2, 2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2053037-A1 | PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER | Sumitomo Chemical Company, Limited (JP) | 2009-04-29 | — | — | EP | disclosed |