Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070011 | 0.89 | DRD2 (0.32) | DRD2 | |
| SCHEMBL1777188 | 0.85 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL7768276 | 0.81 | GABRA1 (0.32) | DRD2 | |
| SCHEMBL1777124 | 0.81 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL185419 | 0.80 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL820424 | 0.77 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL1776374 | 0.76 | — | — | |
| SCHEMBL17388930 | 0.76 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL819446 | 0.75 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL1777267 | 0.75 | KCNH2 (0.50) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169106-A | Antiarrhythmic N,N'-bis(phenylcarbamoylalkyl)amidines | COOPER LABORATORIES, INC. (US) | 1979-09-25 | — | — | US | disclosed |