Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596471 | 0.89 | — | — | |
| SCHEMBL13684848 | 0.81 | KMT2A (0.96) | MEN1KMT2AALDH1A1CYP3A4TP53 | |
| SCHEMBL11842060 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TP53HTTPKM | |
| SCHEMBL491492 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TP53HTTPKM | |
| SCHEMBL11597254 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TP53HTTPKM | |
| SCHEMBL19420513 | 0.79 | KMT2A (0.76) | MEN1KMT2AALDH1A1CYP3A4TP53 | |
| SCHEMBL19420702 | 0.79 | KMT2A (0.76) | MEN1KMT2AALDH1A1CYP3A4TP53 | |
| SCHEMBL27910552 | 0.79 | KMT2A (1.00) | MEN1KMT2AALDH1A1CYP3A4HTT | |
| SCHEMBL26115544 | 0.79 | HTT (0.96) | MEN1KMT2AALDH1A1CYP3A4TP53 | |
| SCHEMBL11596690 | 0.78 | KMT2A (0.84) | MEN1KMT2AALDH1A1CYP3A4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159328-A | INSECTICIDES, MITICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1979-06-26 | — | — | US | disclosed |
| US-4125614-A | DIURETIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-4083979-A | Thiazolidine derivatives and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-4061761-A | Thiazolidine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |