Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 11/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643484 | 0.83 | RAB9A (0.46) | TDP1BRD4CREBBPKDM4EPOLB | |
| SCHEMBL11507934 | 0.80 | TDP1 (0.42) | TDP1KDM4EMAPK1ALDH1A1GAA | |
| SCHEMBL11506314 | 0.77 | KDM4E (0.44) | TDP1BRD4CREBBPKDM4EPOLB | |
| SCHEMBL13266254 | 0.75 | TDP1 (0.46) | TDP1BRD4CREBBPMAPTMAOA | |
| SCHEMBL11506396 | 0.74 | TDP1 (0.53) | TDP1CREBBPKDM4EPOLBMAPT | |
| SCHEMBL11507390 | 0.72 | BRD4 (0.40) | TDP1BRD4CREBBPKDM4EPOLB | |
| SCHEMBL9329830 | 0.68 | PARP1 (0.58) | TDP1BRD4CREBBPKDM4EPOLB | |
| SCHEMBL18126609 | 0.68 | SMN1; SMN2 (0.41) | KDM4EMAOAMAOBALDH1A1GAA | |
| SCHEMBL11505762 | 0.68 | TDP1 (0.49) | TDP1KDM4EMAPK1ALDH1A1GAA | |
| SCHEMBL19961804 | 0.68 | ALDH1A1 (0.49) | KDM4EPOLBMAPTMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143055-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS | GRUPPO LEPETIT S.P.A. (IT) | 1979-03-06 | — | — | US | disclosed |