SCHEMBL1150652

SCHEMBL1150652

CCCCCCOC(=O)[C@H]1[C@H](C=O)C1(C)C

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
NAAA Q02083 1/20 0.43
HCAR2 Q8TDS4 2/20 0.41
EPHX1 P07099 1/20 0.41
TSHR P16473 3/20 0.40
PPARG P37231 3/20 0.39
RAD52 P43351 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
FAAH O00519 1/20 0.37
ALDH1A1 P00352 1/20 0.37
ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2127665 1.00 LMNA (0.46) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL1150645 1.00 LMNA (0.46) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL1150644 1.00 LMNA (0.46) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL2128181 1.00 LMNA (0.46) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL2126033 1.00 LMNA (0.46) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL1149789 0.98 LMNA (0.47) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL1149791 0.98 LMNA (0.47) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL1149793 0.98 LMNA (0.47) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL1150263 0.94 LMNA (0.49) LMNANAAAHCAR2EPHX1TSHR
SCHEMBL357783 0.94 LMNA (0.49) LMNANAAAHCAR2EPHX1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7893294-B2 Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-02-22 US disclosed
US-20090314987-A1 PROCESS FOR PRODUCTION OF TRANS-2, 2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-12-24 US disclosed
EP-2053037-A1 PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER Sumitomo Chemical Company, Limited (JP) 2009-04-29 EP disclosed