Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022459 | 1.00 | PYGB (0.56) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL11029872 | 1.00 | PYGB (0.56) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL3341237 | 1.00 | PYGB (0.56) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL11024009 | 1.00 | PYGB (0.56) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL11425370 | 0.99 | PYGB (0.54) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL11425378 | 0.99 | PYGB (0.54) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL11432138 | 0.99 | PYGB (0.54) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL10797204 | 0.87 | PYGB (0.57) | PYGBGAATSHRKDM4ELMNA | |
| SCHEMBL11515886 | 0.86 | KDM4E (0.46) | PYGBGAAADRA2APDE4AADRA1A | |
| SCHEMBL11515880 | 0.86 | KDM4E (0.46) | PYGBGAAADRA2APDE4AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086415-A | ANTILEUKEMIA, ANTITUMOR | Suami, Tetsuo (JA) | 1978-04-25 | — | — | US | claimed |
| US-4180655-A | ANTITUMOR AND ANTILEUKEMIA AGENTS | Suami, Tetsuo (JP) | 1979-12-25 | — | — | US | disclosed |
| US-4086415-A | ANTILEUKEMIA, ANTITUMOR | Suami, Tetsuo (JA) | 1978-04-25 | — | — | US | disclosed |