SCHEMBL3341237

SCHEMBL3341237

O=NN(CCCl)C(=O)N[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYGB P11216 7/20 0.56
GAA P10253 1/20 0.49
ADRA2A P08913 2/20 0.48
PDE4A P27815 1/20 0.48
ADRA1A P35348 1/20 0.48
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.43
ABCB11 O95342 1/20 0.43
GSR P00390 1/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
AKR1B1 P15121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11507331 1.00 PYGB (0.56) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL11022459 1.00 PYGB (0.56) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL11029872 1.00 PYGB (0.56) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL11024009 1.00 PYGB (0.56) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL11425370 0.99 PYGB (0.54) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL11425378 0.99 PYGB (0.54) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL11432138 0.99 PYGB (0.54) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL10797204 0.87 PYGB (0.57) PYGBGAATSHRKDM4ELMNA
SCHEMBL11515886 0.86 KDM4E (0.46) PYGBGAAADRA2APDE4AADRA1A
SCHEMBL11515880 0.86 KDM4E (0.46) PYGBGAAADRA2APDE4AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6864272-B2 Method and composition for treating cancer using cellular organelle crystallizing agents KONG QINGZHONG (US) 2005-03-08 US claimed
US-4086415-A ANTILEUKEMIA, ANTITUMOR Suami, Tetsuo (JA) 1978-04-25 US claimed
US-20230241282-A1 FOAM COMPOSITIONS, FOAM MATRICES AND METHODS COVALON TECHNOLOGIES INC. (CA) 2023-08-03 US disclosed
US-11517644-B2 Foam compositions, foam matrices and methods COVALON TECHNOLOGIES INC. (CA) 2022-12-06 US disclosed
US-20100162416-A1 Multi-stage stem cell carcinogenesis STEMLIFELINE, INC. (US) 2010-06-24 US disclosed
WO-2010037134-A2 MULTI-STAGE STEM CELL CARCINOGENESIS STEMLIFELINE, INC. (US) 2010-04-01 WO disclosed
US-4593090-A Containing perhydrofuran or pyran ring structure GOGO KIMURA (JP) 1986-06-03 US disclosed
EP-0067019-B1 NOVEL NITROSOUREA COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Kimura, Goro (JP) 1986-03-19 EP disclosed
EP-0056458-B1 NITROSOUREA DERIVATIVES, A PROCESS FOR PREPARING SAME AND THERAPEUTIC COMPOSITIONS Tanabe Seiyaku Co., Ltd. (JP) 1985-05-02 EP disclosed
EP-0062329-B1 NOVEL NITROSOUREA DERIVATIVE, PROCESS FOR PREPARING SAME AND THERAPEUTIC COMPOSITION CONTAINING SAID DERIVATE Tanabe Seiyaku Co., Ltd. (JP) 1985-02-20 EP disclosed
US-4472379-A ANTILEUKEMIA AGENTS SUAMI T (JP) 1984-09-18 US disclosed
US-4251515-A ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA SUAMI T 1981-02-17 US disclosed
US-4241053-A ANTICARCONIGENIC AGENTS, ANTILEUKEMIC AGENT TANABE SEIYAKU CO., LTD. (JP) 1980-12-23 US disclosed
US-4241052-A ANTILEUKEMIC AND ANTICARCINOGENIC AGENTS TANABE SEIYAKU CO., LTD. (JP) 1980-12-23 US disclosed
US-4220643-A ANTITUMOR AGENT AND INHIBITORY ACTIVITY AGAINST LEUKEMIA; LOW TOXICITY SUAMI T (JP) 1980-09-02 US disclosed
US-4182757-A Novel nitrosourea compounds and process for preparing the same TANABE SEIYAKU CO., LTD. (JP) 1980-01-08 US disclosed
US-4180655-A ANTITUMOR AND ANTILEUKEMIA AGENTS Suami, Tetsuo (JP) 1979-12-25 US disclosed
US-4157439-A ANTITUMOR, LOW TOXICITY, NONHYDROLYZING SUAMI T (JP) 1979-06-05 US disclosed
US-4156777-A FROM AN AMINO-GLUCOPYRANOSE AND O-NITRO OR -CYANO-PHENYL N-SUBSTITUTED-N-NITROSOCARBAMATE; ANTITUMOR AGENTS TOKYO TANABE COMPANY, LIMITED (JP) 1979-05-29 US disclosed
US-4086415-A ANTILEUKEMIA, ANTITUMOR Suami, Tetsuo (JA) 1978-04-25 US disclosed