Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.80 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820535 | 0.86 | KMT2A (0.64) | KMT2AMCOLN3PKMSMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3122697 | 0.85 | KMT2A (0.62) | KMT2AMCOLN3PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL2959210 | 0.79 | ALDH1A1 (0.66) | KMT2APKMSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11508483 | 0.79 | PKM (0.60) | KMT2AMCOLN3PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL18362596 | 0.78 | PKM (0.51) | KMT2AMCOLN3PKMSMN1; SMN2L3MBTL1 | |
| SCHEMBL10571161 | 0.78 | KMT2A (0.64) | KMT2AMCOLN3SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10573633 | 0.78 | KMT2A (0.64) | KMT2AMCOLN3ALDH1A1GAATSHR | |
| SCHEMBL2821332 | 0.78 | KMT2A (0.75) | KMT2APKMSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1352340 | 0.77 | PKM (0.77) | KMT2APKMSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL16814147 | 0.77 | MAPT (0.51) | KMT2AMCOLN3PKMSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159331-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |