SCHEMBL11509136

SCHEMBL11509136

CCCC1Nc2cccc3cccc(c23)N1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 19/20 0.49
KMT2A Q03164 19/20 0.49
NPC1 O15118 6/20 0.47
GAA P10253 8/20 0.46
ALDH1A1 P00352 6/20 0.45
MAPT P10636 6/20 0.45
KDM4E B2RXH2 5/20 0.45
POLB P06746 2/20 0.45
HPN P05981 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
THRB P10828 3/20 0.44
HPGD P15428 3/20 0.44
RAB9A P51151 2/20 0.44
USP2 O75604 2/20 0.44
ALOX15 P16050 2/20 0.44
MAPK1 P28482 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
LMNA P02545 1/20 0.44
MCL1 Q07820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11333477 0.87 MEN1 (0.46) MEN1KMT2ANPC1GAAALDH1A1
SCHEMBL10924390 0.86 MEN1 (0.44) MEN1KMT2ANPC1GAAALDH1A1
SCHEMBL10607509 0.76 MEN1 (0.43) MEN1KMT2ANPC1GAAALDH1A1
SCHEMBL16535647 0.75 MEN1 (0.50) MEN1KMT2ANPC1GAAALDH1A1
SCHEMBL3691928 0.75 MEN1 (0.33) MEN1KMT2ANPC1ALDH1A1MAPT
SCHEMBL13476562 0.74 CREBBP (0.41) MEN1KMT2AALDH1A1
SCHEMBL16223065 0.73 MEN1 (0.44) MEN1KMT2ANPC1GAAALDH1A1
SCHEMBL10078299 0.73 MEN1 (0.55) MEN1KMT2ANPC1GAAALDH1A1
SCHEMBL9251298 0.72 MEN1 (0.49) MEN1KMT2ANPC1GAAALDH1A1
SCHEMBL15018809 0.71 MEN1 (0.39) MEN1KMT2ANPC1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179395-A LIQUID CRYSTALS FOR USE IN DISPLAYS GENERAL ELECTRIC COMPANY (US) 1979-12-18 US disclosed
US-4128497-A TRISAZO DYE GENERAL ELECTRIC COMPANY (US) 1978-12-05 US disclosed