Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 20/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 20/20 | 0.49 |
| ▸ | GAA | P10253 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014670 | 0.75 | MEN1 (0.43) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL9251303 | 0.75 | ALDH1A1 (0.43) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL11509136 | 0.72 | MEN1 (0.49) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL1083163 | 0.71 | TNKS2 (0.46) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL11333477 | 0.68 | MEN1 (0.46) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL16223065 | 0.68 | MEN1 (0.44) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL10078299 | 0.67 | MEN1 (0.55) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL15040890 | 0.67 | MEN1 (0.55) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL13330038 | 0.67 | MEN1 (0.55) | MEN1KMT2AGAANPC1POLB | |
| SCHEMBL27894628 | 0.67 | MEN1 (0.50) | MEN1KMT2AGAANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406812-A2 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INCORPORATED (US) | 1991-01-09 | — | — | EP | claimed |
| EP-0406812-B1 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INC (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0406812-A2 | Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine | HERCULES INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |