SCHEMBL11509596

SCHEMBL11509596

Cc1nc(S(C)(=O)=O)nc(N)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 1/20 0.38
TLR7 Q9NYK1 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
IDO1 P14902 1/20 0.35
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
MAPK1 P28482 2/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TLR9 Q9NR96 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13754207 0.84 LMNA (0.41) GLP1RSMN1; SMN2LMNACA12CA2
SCHEMBL10514950 0.78 LMNA (0.38) GLP1RTLR7SMN1; SMN2LMNAIDO1
SCHEMBL7754111 0.78 LMNA (0.38) SMN1; SMN2LMNACA12CA2CA9
SCHEMBL11426170 0.78 PDE10A (0.47) GLP1RTLR7SMN1; SMN2LMNAMAPK1
SCHEMBL7753498 0.77 SMN1; SMN2 (0.36) GLP1RSMN1; SMN2LMNACA12CA2
SCHEMBL18067288 0.75 LMNA (0.35) GLP1RTLR7SMN1; SMN2LMNACA12
SCHEMBL11509593 0.75 LMNA (0.35) SMN1; SMN2LMNACA12CA2CA9
SCHEMBL6250177 0.75 LMNA (0.35) SMN1; SMN2LMNACA12CA2CA9
SCHEMBL18893674 0.72 GLP1R (0.36) GLP1RTLR7SMN1; SMN2LMNAALDH1A1
SCHEMBL9432620 0.72 SMN1; SMN2 (0.47) SMN1; SMN2LMNACA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4169705-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-10-02 US disclosed
US-4153413-A DYEING POLYESTER OR CELLULOSE TRIACETATE WITH A DISPERSE AZO DYESTUFF, HEAT TREATMENT, PADDING, PRINTING IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-05-08 US disclosed
US-4147510-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-04-03 US disclosed
US-4134723-A DYEING AROMATIC POLYESTER/POLYAMIDE OR AROMATIC POLYESTER/CELLULOSE BLENDS WITH DISPERSE MONOAZO DYE, ALKALINE BATH IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-01-16 US disclosed