SCHEMBL7754111

SCHEMBL7754111

Cc1nc(S(C)(=O)=O)nc(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA12 O43570 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
XBP1 P17861 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TLR9 Q9NR96 1/20 0.33
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
SDHB P21912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25859859 0.88 SMN1; SMN2 (0.41) LMNASMN1; SMN2ALDH1A1NPC1TP53
SCHEMBL13754207 0.88 LMNA (0.41) LMNASMN1; SMN2CA12CA2CA9
SCHEMBL9625868 0.82 LMNA (0.38) LMNASMN1; SMN2CA12CA2CA9
SCHEMBL10123082 0.81 LMNA (0.40) LMNASMN1; SMN2CA12CA2CA9
SCHEMBL7753498 0.80 SMN1; SMN2 (0.36) LMNASMN1; SMN2CA12CA2CA9
SCHEMBL10584229 0.80 LMNA (0.36) LMNASMN1; SMN2
SCHEMBL9626462 0.78 LMNA (0.35) LMNASMN1; SMN2CA12CA2CA9
SCHEMBL12036842 0.78 SMN1; SMN2 (0.35) LMNASMN1; SMN2CA12CA2CA9
SCHEMBL29472136 0.78 LMNA (0.35) LMNASMN1; SMN2CA12CA2CA9
SCHEMBL10354234 0.78 LMNA (0.36) LMNASMN1; SMN2NPC1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5378574-A Inks and liquid developers containing colored silica particles XEROX CORPORATION (US) 1995-01-03 US claimed
US-5102763-A Hydrophilic particles with dyes covalently bonded to surface through silane coupling agent XEROX CORPORATION (US) 1992-04-07 US claimed
US-5100471-A Liquid ink compositions XEROX CORPORATION (US) 1992-03-31 US claimed
US-5098475-A Inks with dendrimer colorants XEROX CORPORATION (US) 1992-03-24 US claimed
US-4877451-A Ink jet inks containing colored silica particles XEROX CORPORATION (US) 1989-10-31 US claimed
EP-1068390-A1 METHOD FOR IMPROVED WET STRENGTH PAPER Kimberly-Clark Worldwide, Inc. (US) 2001-01-17 EP disclosed
EP-0778322-B1 Ink compositions containing liposomes XEROX CORP (US) 2000-05-17 EP disclosed
WO-1999045201-A1 METHOD FOR IMPROVED WET STRENGTH PAPER KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-09-10 WO disclosed
US-5935383-A Method for improved wet strength paper KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-08-10 US disclosed
EP-0778322-A2 Ink compositions containing liposomes XEROX CORPORATION (US) 1997-06-11 EP disclosed
US-5626654-A DYE WITH VESICLE FORMING LIPID FOR INKS, MEMBRANES OF LIPIDS BONDED BY POLYMERIZATION PROCESS XEROX CORPORATION (US) 1997-05-06 US disclosed
EP-0355062-B1 Ink jet inks and liquid developers XEROX CORP (US) 1996-07-24 EP disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4001205-A WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-4001203-A Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-3989692-A PHTHALOCYANINE DYES, WOOL, SILK, POLYAMIDES, CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed
US-3988310-A FIBER-REACTIVE DYES; CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3957751-A WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed
US-3956263-A 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs CIBA-GEIGY AG (CH) 1976-05-11 US disclosed