Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 11/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.34 |
| ▸ | PTGIR | P43119 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509790 | 1.00 | MEN1 (0.42) | MEN1KMT2AGALR3PTGER4PTGER2 | |
| SCHEMBL11246612 | 0.90 | MEN1 (0.45) | MEN1KMT2AGALR3PTGER4PTGER2 | |
| SCHEMBL11246637 | 0.90 | MEN1 (0.45) | MEN1KMT2AGALR3PTGER4PTGER2 | |
| SCHEMBL11246623 | 0.90 | MEN1 (0.45) | MEN1KMT2AGALR3PTGER4PTGER2 | |
| SCHEMBL11509819 | 0.84 | MEN1 (0.36) | MEN1KMT2AGALR3PTGER4PTGER2 | |
| SCHEMBL11509816 | 0.84 | MEN1 (0.36) | MEN1KMT2AGALR3PTGER4PTGER2 | |
| SCHEMBL11258798 | 0.81 | MEN1 (0.34) | MEN1KMT2AGALR3 | |
| SCHEMBL11512188 | 0.81 | ALDH1A1 (0.34) | MEN1KMT2APTGER4PTGER2PTGER3 | |
| SCHEMBL11512185 | 0.81 | ALDH1A1 (0.34) | MEN1KMT2APTGER4PTGER2PTGER3 | |
| SCHEMBL11258802 | 0.81 | MEN1 (0.34) | MEN1KMT2AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144251-A | PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-3959263-A | Prostaglandin intermediate | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |