Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | PTGFR | P43088 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.32 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512185 | 1.00 | ALDH1A1 (0.34) | ALDH1A1PTGFRLMNAHPGDTSHR | |
| SCHEMBL11512271 | 1.00 | ALDH1A1 (0.34) | ALDH1A1PTGFRLMNAHPGDTSHR | |
| SCHEMBL11531750 | 0.89 | PTGFR (0.31) | PTGFR | |
| SCHEMBL11431471 | 0.84 | ALDH1A1 (0.40) | ALDH1A1PTGFRLMNAHPGDTSHR | |
| SCHEMBL11776725 | 0.83 | ALDH1A1 (0.39) | ALDH1A1PTGFRLMNAHPGDTSHR | |
| SCHEMBL11591221 | 0.82 | MEN1 (0.39) | ALDH1A1PTGFRLMNAHPGDTSHR | |
| SCHEMBL11736544 | 0.82 | MEN1 (0.39) | ALDH1A1PTGFRLMNAHPGDTSHR | |
| SCHEMBL11594713 | 0.82 | MEN1 (0.39) | ALDH1A1PTGFRLMNAHPGDTSHR | |
| SCHEMBL11746902 | 0.81 | — | — | |
| SCHEMBL11509792 | 0.81 | MEN1 (0.42) | PTGFRLMNAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144251-A | PROSTAGLANDINS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-3959263-A | Prostaglandin intermediate | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |