Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508770 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL28402993 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL29364937 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL231377 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL11510484 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL28520448 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL2809853 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL2810654 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL11509544 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1MAPTKMT2A | |
| SCHEMBL27868359 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147802-A | TREATMENT WITH AMINOCARBONYL SUBSTITUTED PARAAMINOBENZOIC ACID | STANLEY DRUG PRODUCTS, INC. (US) | 1979-04-03 | — | — | US | claimed |
| US-4147802-A | TREATMENT WITH AMINOCARBONYL SUBSTITUTED PARAAMINOBENZOIC ACID | STANLEY DRUG PRODUCTS, INC. (US) | 1979-04-03 | — | — | US | disclosed |