Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559750 | 0.82 | HSP90AB1 (0.48) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL28524236 | 0.80 | MAPT (0.41) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL11509832 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL29105091 | 0.76 | RAPGEF4 (0.45) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL715406 | 0.76 | KDM4E (0.65) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL7409099 | 0.76 | MAPT (0.48) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL8759303 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL3181880 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL6030557 | 0.74 | KDM4E (0.63) | ALDH1A1KDM4ETDP1MAPTCYP3A4 | |
| SCHEMBL6030346 | 0.74 | KDM4E (0.63) | ALDH1A1KDM4ETDP1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459281-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-05-16 | — | — | CN | disclosed |