Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073759 | 0.87 | TDP1 (0.54) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL10584939 | 0.81 | CYP3A4 (0.60) | TSHRMAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL10587058 | 0.80 | CYP3A4 (0.58) | TSHRMAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL1951190 | 0.78 | CYP2C9 (0.50) | TSHRMAPK1ALDH1A1NQO1CYP2C9 | |
| SCHEMBL17400969 | 0.77 | NQO1 (0.61) | TDP1TSHRALDH1A1NQO1RAB9A | |
| SCHEMBL8942095 | 0.77 | TDP1 (0.57) | TDP1TSHRMAPK1CYP3A4NQO1 | |
| SCHEMBL16519363 | 0.76 | NQO1 (0.46) | TDP1TSHRALDH1A1CYP3A4NQO1 | |
| SCHEMBL14952746 | 0.75 | KMT2A (0.44) | TDP1TSHRMAPK1ALDH1A1NQO1 | |
| SCHEMBL11272090 | 0.74 | TDP1 (0.53) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL5779539 | 0.74 | USP2 (0.45) | TSHRCYP3A4NQO1SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143228-A | RED SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |