SCHEMBL5779539

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17400969	0.88	NQO1 (0.61)	TSHRNQO1KDM4EMAPTSMN1; SMN2
	SCHEMBL16519363	0.86	NQO1 (0.46)	TSHRNQO1KDM4ECYP1A2CYP3A4
	SCHEMBL1951190	0.84	CYP2C9 (0.50)	TSHRNQO1MEN1KMT2AKDM4E
	SCHEMBL3776385	0.82	LTA4H (0.48)	TSHRNQO1KDM4ECYP1A2CYP3A4
	SCHEMBL20539545	0.82	APP (0.44)	TSHRNQO1PPARA
	SCHEMBL2334467	0.82	SCN4A (0.46)	NQO1FFAR1CYP1A2MAPTPPARG
	SCHEMBL17400983	0.82	NQO1 (0.43)	NQO1MEN1KMT2ALMNAMAPT
	SCHEMBL2329756	0.82	CYP1A2 (0.47)	TSHRNQO1MEN1KMT2ADRD2
	SCHEMBL2329778	0.82	KDM4E (0.46)	USP2TSHRNQO1MEN1KMT2A
	SCHEMBL1193076	0.82	LMNA (0.53)	LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.