Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20043278 | 0.85 | HSD17B10 (0.41) | HSD17B10ALDH1A1MAPTRAB9ANUDT1 | |
| SCHEMBL4918805 | 0.83 | PIK3CA (0.50) | HSD17B10PIK3CAPI4KAPI4KBALDH1A1 | |
| SCHEMBL1806582 | 0.78 | ALDH1A1 (0.56) | HSD17B10PIK3CAPI4KAPI4KBALDH1A1 | |
| SCHEMBL2274638 | 0.76 | HSD17B10 (0.50) | HSD17B10ALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL1913640 | 0.75 | HSD17B10 (1.00) | HSD17B10ALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL21091214 | 0.75 | HSD17B10 (0.72) | HSD17B10ALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL23629009 | 0.75 | ALDH1A1 (0.53) | HSD17B10ALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL21089486 | 0.75 | ALDH1A1 (0.47) | HSD17B10PIK3CAPI4KAPI4KBALDH1A1 | |
| SCHEMBL4846424 | 0.74 | ALDH1A1 (0.60) | HSD17B10ALDH1A1MAPTRAB9ALMNA | |
| SCHEMBL9474148 | 0.74 | CYP3A4 (0.55) | HSD17B10PIK3CAPI4KAPI4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136033-A | DIAZO COUPLERS | SANDOZ LTD. (CH) | 1979-01-23 | — | — | US | disclosed |