Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.55 |
| ▸ | SCN4A | P35499 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474741 | 0.80 | CYP3A4 (0.59) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9474613 | 0.80 | RAB9A (0.50) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL4436885 | 0.78 | NPC1 (0.48) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9475114 | 0.77 | HSD17B10 (0.57) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9185915 | 0.77 | CYP3A4 (0.56) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL4918805 | 0.76 | PIK3CA (0.50) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| Bromide SCHEMBL9189616 | 0.76 | CYP3A4 (0.55) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9475348 | 0.75 | CYP3A4 (0.54) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9188493 | 0.75 | CYP3A4 (0.54) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL9476104 | 0.74 | CYP3A4 (0.52) | CYP3A4NPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236940-A | Administering for treatment of medical conditions associated with the effects of glutamate; glutamate-induced convulsions; schizophrenia; sleep disorders | RHONE-POULENC SANTE (FR) | 1993-08-17 | — | — | US | disclosed |