Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510342 | 0.86 | CA12 (0.61) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL10782516 | 0.83 | CA12 (0.88) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL11512368 | 0.78 | MAPT (0.59) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL11509284 | 0.76 | MAPT (1.00) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL11510302 | 0.76 | EGFR (0.72) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL11512342 | 0.75 | KDM4E (0.66) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL11511257 | 0.75 | MAOB (0.62) | MAPTALDH1A1TYRMAOBTDP1 | |
| SCHEMBL6340490 | 0.75 | CA12 (0.51) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL14521268 | 0.74 | TYR (0.62) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL11514456 | 0.74 | MAPT (0.70) | CA12CA2CA9MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |