Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | USP10 | Q14694 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517426 | 0.93 | VCAM1 (0.46) | POLBMAPTVCAM1MAPK1ALDH1A1 | |
| SCHEMBL574446 | 0.91 | VCAM1 (0.44) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL574447 | 0.91 | VCAM1 (0.44) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL10224543 | 0.91 | VCAM1 (0.44) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL10222900 | 0.91 | VCAM1 (0.46) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL573657 | 0.91 | VCAM1 (0.46) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL574029 | 0.91 | VCAM1 (0.46) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL11509690 | 0.86 | VCAM1 (0.43) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL11512108 | 0.86 | MAPT (0.45) | POLBMAPTVCAM1ALDH1A1HPGD | |
| SCHEMBL11002863 | 0.86 | MAPT (0.44) | POLBMAPTVCAM1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172142-A | DIURETICS FOR TREATMENT OF EDEMA | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |