Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821599 | 1.00 | TDP1 (0.76) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL9329294 | 0.98 | TDP1 (0.79) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL25305081 | 0.95 | TDP1 (0.69) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL7297778 | 0.93 | TDP1 (0.75) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11896606 | 0.89 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL2069111 | 0.89 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL223238 | 0.89 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL17466182 | 0.89 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL225815 | 0.89 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11896235 | 0.89 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028746-A1 | METHOD FOR THE DECARBOXYLATIVE HYDROFORMYLATION OF ALPHA, BETA- UNSATURATED CARBOXYLIC ACIDS | BASF SE (DE) | 2011-02-03 | — | — | US | disclosed |
| US-5081287-A | Pesticidal polyhalo alkenoic acid esters | FMC CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028746-A1 | METHOD FOR THE DECARBOXYLATIVE HYDROFORMYLATION OF ALPHA, BETA- UNSATURATED CARBOXYLIC ACIDS | PCCA, CBR3, CBR1 | TDP1 4504/4885LMNA 493/4885ALDH1A1 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.