Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821599 | 0.98 | TDP1 (0.76) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL1151086 | 0.98 | TDP1 (0.76) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL7297778 | 0.95 | TDP1 (0.75) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL25305081 | 0.94 | TDP1 (0.69) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL2844201 | 0.89 | TDP1 (0.66) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL223441 | 0.89 | TDP1 (1.00) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL17466182 | 0.87 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL2069111 | 0.87 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11896606 | 0.87 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL223238 | 0.87 | TDP1 (0.96) | TDP1LMNAALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118995467-A | Producing strain of 5-ketomilbemycins and application thereof | 浙江海正药业股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2014126802-A1 | ALKENE AZETIDINE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| CN-1040434-C | Heterobicyclic compounds | RECORDATI CHEM PHARM (CH) | 1998-10-28 | — | — | CN | disclosed |
| US-5304549-A | Control or prevention of degenerative joint diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-04-19 | — | — | US | disclosed |
| CN-1079738-A | Heterobicyclic compounds | RECORDATI CHEM PHARM (CH) | 1993-12-22 | — | — | CN | disclosed |
| US-5248810-A | Insecticides, acaricides | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-28 | — | — | US | disclosed |
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |
| CN-1053054-A | The preparation method of halogenated olefine and as desinsection and acaricidal application | SCHERING AG (DE) | 1991-07-17 | — | — | CN | disclosed |
| EP-0432861-A1 | Halogenated olefines, process for the preparation thereof and their use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-19 | — | — | EP | disclosed |