Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30691783 | 0.87 | HTT (0.58) | HTTLMNAGAAL3MBTL1PPARA | |
| SCHEMBL20804371 | 0.84 | HTT (0.61) | HTTL3MBTL1KCNH3PTPN1PTPRZ1 | |
| SCHEMBL11015099 | 0.84 | HPGD (0.63) | LMNAGAAL3MBTL1PPARASMN1; SMN2 | |
| SCHEMBL26980175 | 0.83 | L3MBTL1 (0.49) | HTTLMNAL3MBTL1KCNH3MAPT | |
| Hydrochloric Acid SCHEMBL27774106 | 0.82 | HPGD (0.61) | LMNAGAAL3MBTL1PPARAKCNH3 | |
| SCHEMBL4241915 | 0.81 | HTT (0.64) | HTTLMNAGAAL3MBTL1KCNH3 | |
| SCHEMBL11935972 | 0.80 | PPARA (0.49) | HTTPPARAGPR68KCNH3HPGD | |
| SCHEMBL6772345 | 0.80 | KCNH2 (0.56) | HTTLMNAGAAL3MBTL1KCNH3 | |
| SCHEMBL8447034 | 0.80 | NOS2 (0.47) | HTTMAPTHPGDALDH1A1CYP1A2 | |
| SCHEMBL13513332 | 0.77 | HDAC4 (0.53) | LMNAPPARAALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314624-B | Preparation method of polyfluoroaniline | 东莞东阳光科研发有限公司 | 2022-09-27 | — | — | CN | disclosed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| CN-109071374-A | The arylation of fatty amine | AAA化学公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-3414216-A1 | ARYLATION OF ALIPHATIC AMINES | AAA Chemistry ApS (DK) | 2018-12-19 | — | — | EP | disclosed |
| CN-108314624-A | A kind of preparation method of polyfluoro aniline | 东莞东阳光科研发有限公司 | 2018-07-24 | — | — | CN | disclosed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | disclosed |
| US-4152452-A | N-BENZYLANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1979-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | NAT1, AHR, ABL1 | HTT 734/4885LMNA 2612/4885GAA 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.