Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508615 | 0.89 | TAS1R3 (0.59) | TAS1R3TAS1R1LMNANPSR1ALDH1A1 | |
| SCHEMBL11508045 | 0.87 | TAS1R3 (0.58) | TAS1R3TAS1R1LMNAMAPK1NPSR1 | |
| SCHEMBL11509367 | 0.87 | TAS1R3 (0.62) | TAS1R3TAS1R1LMNANPSR1ALDH1A1 | |
| SCHEMBL26814843 | 0.81 | TAS1R3 (0.64) | TAS1R3TAS1R1LMNAMAPK1NPSR1 | |
| SCHEMBL16234929 | 0.81 | TRPA1 (0.56) | TAS1R3TAS1R1LMNAMAPK1NPSR1 | |
| SCHEMBL26820886 | 0.79 | TAS1R3 (0.70) | TAS1R3TAS1R1LMNANPSR1ALDH1A1 | |
| SCHEMBL31595936 | 0.78 | TAS1R3 (0.64) | TAS1R3TAS1R1LMNANPSR1ALDH1A1 | |
| SCHEMBL16235094 | 0.77 | TRPA1 (0.66) | LMNAMAPK1ALDH1A1HTTTRPA1 | |
| SCHEMBL27564141 | 0.77 | HTT (0.56) | LMNAMAPK1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11509188 | 0.77 | NPSR1 (0.66) | TAS1R3TAS1R1LMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161529-A | Phenoxy phenyl pyrrolidine compounds, compositions and methods of use | SCIENCE UNION ET CIE, SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1979-07-17 | — | — | US | disclosed |